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KMID : 1100920210420020150
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Korean Journal of Family Medicine
2021 Volume.42 No. 2 p.150 ~ p.158
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Determining the Prevalence of and the Factors Associated with Antihypertensive Medication Non-Adherence in the Gaza Strip
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Khadoura Khalid
Shakibazadeh Elham
Mansournia Mohammad Ali
Aljeesh Yousef
Fotouhi Akbar
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Abstract
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Background: This study aimed to estimate the prevalence of and determine the factors associated with antihypertensive medication (A-HTNM) non-adherence among hypertension care seekers attending primary health clinics in the Gaza Strip.
Methods: A cross-sectional survey was conducted as the recruitment phase of a clustered randomized controlled trial including 538 participants. The participants were randomly selected from 10 primary health care centers by two-stage cluster random sampling. A structured questionnaire was used to collect data through face-to-face interview. The questionnaire was developed based on the World Health Organization determinants for medication non-adherence and the Health Belief Model. The main outcomes of this study were the prevalences of A-HTNM non-adherence and its associated factors. Adherence status was assessed using the eight-item Morisky Self-Report Medication Adherence Scale. Data were analyzed by STATA ver. 14.0 (Stata Corp., College Station, TX, USA) using a standard complex survey, accounting for unresponsiveness and the clustering sampling approach.
Results: The overall prevalence of A-HTNM non-adherence was 65.8% (95% confidence interval [CI], 59.2?71.8). Among all studied predictors, only self-efficacy of participants (odds ratio [OR], 3.8; 95% CI, 1.79?2.84) and social support (OR, 2.26; 95% CI, 2.82?5.11) remained significantly associated with A-HTNM non-adherence after adjusting for age, education level, number and frequency of A-HTNM doses per day, and comorbidities.
Conclusion: The high prevalence of non-adherence highlights the need for serious intervention to enhance the adherence rate among hypertension patients. The associated factors can be considered when developing appropriate interventions.
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KEYWORD
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Antihypertensive Drugs, Medication Non-Adherence, Prevalence
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